Aristo Vojdani PhD - The Gut-Brain Axis in Autoimmune and Neuro

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Topic: The Gut-Brain Axis in Autoimmune and Neuroimmune Disorders by Aristo Vojdani PhD

Conference: A Gut Feeling - Atlanta, GA - March 2 - 6, 2016

Summary: The human body is an incredibly complex system, and since time immemorial man has struggled to work out what exactly his gut and his brain have to do with his health, and whether perhaps the two are connected somehow. The parallels between the gut and brain immune systems are too self-evident to deny. These similarities extend to the actual structures, mechanisms and even biochemistries of the two systems: the gut immune barrier (GIB) and the blood-brain barrier (BBB). Bidirectional signaling between the brain and gut has been confirmed by numerous studies. In fact, this communication between the gut and brain is ongoing from birth, and plays a significant role in shaping how the brain is wired. The gut’s influence on the brain cannot be overestimated, so much so that it can be called a second brain. Studies have linked gut microbiota dysbiosis to brain-linked disorders such as depression, anxiety, multiple sclerosis and autism. There is an awareness now that neurodegenerative diseases may not exclusively have a neurological trigger. Uncontrolled chronic inflammation, disturbances in the gut microbiota and other gastrointestinal-related dysfunctions open the intestinal barrier “leaking” inflammatory agents into the bloodstream. Inflammation from circulating gut-derived lipopolysaccharides, for example, open the BBB and have been linked to neurodegenerative disorders. A spotlight has been focused on the role of intestinal barrier function in the pathogenesis not just of gastrointestinal diseases but of autoimmune, neuroautoimmune and neurodegenerative ones as well. Using predictive antibodies opens the possibility of prevention, amelioration and even reversal of autoimmune disorders, both gastrointestinal and neurodegenerative, through treatment modalities involving the repair of the GIB and BBB, thus restoring their functionality and harmony throughout the body.

Learning Objectives:
1. Apply the gut – immune system – brain connection for better management of chronic disorders.
2. Expertly assess intestinal and blood-brain barrier dysfuctions.
3. Explain the evidence-based use of predictive antibodies for the identification of tissue damage caused by environmental triggers.
4. Identify modern lifestyles and environmental triggers that are affecting the gut-brain axis and contributing to the neuroautoimmune epidemic.
5. Explain how the interaction of the brain and the gut plays a vital role in health and disease.
6. Explain how modern lifestyles and environmental triggers such as bacterial toxins and food antigens can contribute to gut and blood-brain barrier dysfunction, leading to autoimmunities.
7. Identify the distinctions between raw and cooked food and their potential effects on the brain and body.
8. Explain how predictive antibodies can be used to identify environmental triggers and help patients live better lives.

Time: 1 hr. 4 mins.

File Type: Down-loadable Zip file including MP3 audio file and PDF slides.

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